Partner 4

Characterization of the Helicase Activity and Substrate Specificity of Mycobacterium tuberculosis UvrD.
E. Curti, S.J. Smerdon, E.O. Davis J. Bacteriol. 2007, 189, 1542-1555.

The mycobacterial-specific gene Rv2719c is DNA-damage inducible independently of RecA.
P.C. Brooks, L.F. Dawson, L. Rand, E.O. Davis J. Bacteriol. 2006, 188, 6034-6038.

Deletion of the Mycobacterium tuberculosis pknH gene confers a higher bacillary load during the chronic phase of infection in BALB/c mice.
K.G. Papavinasasundaram, B. Chan, J.H. Chung, M.J. Colston, E.O. Davis, Y. Av-Gay J. Bacteriol. 2005, 187, 5751-5760.

The AraC family transcriptional regulator Rv1931c plays a role in the virulence of Mycobacterium tuberculosis
C.C. Frota, K.G. Papavinasasundaram, E.O Davis, M.J. Colston. Infect. Immun. 2004, 72, 5483- 5486.

The majority of inducible DNA repair genes in Mycobacterium tuberculosis are induced independently of RecA.
L. Rand, J. Hinds, B. Springer, P. Sander, R.S. Buxton, E.O. Davis Mol. Microbiol. 2003, 50, 1031-1042.


Title: New Approaches to Target Tuberculosis

Acronym: NATT

Contract number: 222965

EC contribution: 2.994.478 €

Duration: 36 months

Starting date: 01/10/2008

Collaborative project